Hormone effects in smoking addiction

Brief Description Of Study

Healthy male and non-pregnant female smokers are invited to screen for study participation in a protocol examining the effect of the hormone progesterone on smoking cravings.

Clinical Study Identifier: TX1035

Detailed Study Description

Smokers between the ages of 18-50 who smoke at least 10 cigarettes per day will be asked to undergo a screening visit where they sign the informed consent form, complete structured clinical interviews and provide breath and urine samples which will be run for nicotine levels, a drug screen and pregnancy test (for women only). All qualified participants will be asked to participate in two 5-day long out-patient test phases where they will undergo 3 brain-imaging scans and remain abstinent from smoking. Participants can receive up to $800 for full study completion.

Additional Information About The Study

Eligible subjects must: Be female and male smokers, aged 18 to 50 years; Have a history of smoking daily for the past 12 months, 10-25 cigarettes daily; NOT be seeking treatment for nicotine dependence; (for women) have regular menses every 25-35 days; Be in good health as verified by medical history; (for women) NOT be pregnant as determined by pregnant screening, nor breast feeding, and using acceptable birth control methods other than hormonal contraceptives; NOT have a history of a major medical illness; NOT be using psychotropic medication (antidepressants, antipsychotics, or anxiolytics); NOT have a recent diagnosis (within previous year) and treatment for Axis I disorders (major depression, bipolar affective disorder, generalized anxiety disorder, PTSD, and panic disorder); NOT have a lifetime history of schizophrenia or a substance addiction disorder, except nicotine; NOT have substance abuse disorder within previous 2 years, except nicotine; (for women) NOT be using oral contraceptives; NOT be using any other tobacco products other than cigarettes, including smokeless tobacco and nicotine products; NOT have a known allergy to progesterone or peanuts (vehicle for micronized progesterone).

Contact research investigator to learn more about this study by filling out the form below.

To: Research Study Investigator
Subject: I am interested in participating in your Research Study
Dear Investigator,
I'm interested in learning more about and participating in your research study named: Hormone effects in smoking addiction
I am hoping to hear back from you and discuss details of the study

By clicking "Contact Research Team", your contact information will be sent directly to the research staff associated with the study. You will also receive a copy of this email in your inbox, as well as other notifications to determine your participation status in the study.