Optical measurement of Cerebral Blood Flow Response after Ischemic Stroke
Brief Description Of Study
This study is a non-randomized, Phase 2 clinical trial designed to assess optical CBF response to bolus normal saline. Subjects will have had an ischemic stroke within 96 hours of enrollment and no contraindication to bolus normal saline. The study intervention will be a one hour monitoring session. There will be a 15 minute baseline measurement period, followed by intravenous administration of 500cc of 0.9% NaCl over 30 minutes, and finally 15 minutes of monitoring post-bolus. All study measurements will cease after 1 hour. Subjects will be followed during their hospitalization for 7 days or until discharge, whichever is sooner, to monitor for adverse events and to collect relevant clinical information.