Efficacy of DE-MRI-Guided Ablation vs. Conventional Catheter Ablation of Atrial Fibrillation: The DECAAF II Study
DECAAF II is a prospective, randomized, multi-center trial of patients with persistent AF and presence of atrial brosis. After consenting to participate in the study, the subject will undergo a DE-MRI scan to assess for extent of atrial brosis. After verifying adequate quality of the DE-MRI study, subjects will be randomized to one of two study groups to receive conventional PVI ablation (Group 1) or PVI+brosis-guided ablation (Group 2), as summarized in Figure 1 on the following page. In Group 1, PVI ablation will be performed as recommended by the HRS consensus statement2 and physicians will be blinded to the pre-ablation MRI brosis results. In Group 2, physicians will receive the DE-MRI scan prior to the ablation procedure, will complete conventional PV isolation,and will also target left atrial brosis detected by MRI.
- Study Identifier: 823595
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