Glucose Counterregulation in Long Standing Type 1 Diabetes (PRIME)
We are in the final phase of this study and are searching for a Hypo-AWARE Type 1 diabetic control group (Group 2) The primary goal for Group 2 in this study is to show us how hormones of Type 1 diabetics should react during hypoglycemic and non-hypoglycemic events. Participants can ...
Determination of B-cell responsiveness to the incretin hormones GLP-1 and GIP in Cystic Fibrosis (PRIME)
The mechanisms underlying cystic fibrosis related diabetes (CFRD) pathophysiology must be better defined if care for people with CFRD is to be optimized or if development of CFRD is to be interrupted. Detailed studies of insulin secretion in CF are required to achieve this goal since 1) subtle insulin secretion ...
Evaluation of the Enteroinsular Axis in Cystic Fibrosis (CHOP IRB #: 12-009589)
Cardiovascular Inflammation Reduction Trial (CIRT): A randomized double-blind placebo controlled event-driven trial of weekly low-dose methotrexate (LDM) in the prevention of recurrent cardiovascular events among stable post-myocardial infarction patients with type 2 diabetes or metabolic syndrome
This is an event-driven, multi-center, randomized, double-blind, placebo-controlled trial to determine whether methotrexate reduces heart attacks, strokes, or death in people who have already had at least one heart attack and have type 2 diabetes or metabolic syndrome. Metabolic syndrome is defined as a combination of problems including a large ...
The Type 1 Diabetes Exchange Clinic-based Registry Network
T1D Exchange is a nonprofit program dedicated to improving the lives of people touched by type 1 diabetes (T1D). This program has been developed in collaboration with government agencies, JDRF, ADA, the Helmsley Charitable Trust, Clinicians, industry and people living with T1D with the overall goal of improving health outcomes. ...
Primary Cell Core