Normal Donor Human Bone Marrow Donation for Research
We are looking for healthy volunteers to donate bone marrow for research purposes. The Stem Cell & Xenograft Core provides bone marrow to laboratories on Penn’s campus researching leukemia and other blood disorders
Eye and Brain Connections: MRI Study of Normal-Sighted Controls
The goal of this study is to better understand how visual information reaches the brain and how this process changes over time. Using advanced MRI methodology we will examine structure and function of visual pathways within the brain to gain deeper understanding of how people with low vision are able ...
Hormone effects in smoking addiction
Healthy male and non-pregnant female smokers are invited to screen for study participation in a protocol examining the effect of the hormone progesterone on smoking cravings.
T-Cell Response to Vaccination
The purpose of this study is to see how your body responds to a vaccine and how your body forms a protective response after vaccination. In this study we will use the yellow fever vaccine, an FDA approved vaccine that is commonly given to people traveling to certain parts of ...
A study to understand how the brain develops and changes in people ages 10 - 30
The purpose of this study is to examine the brain and behavior as it relates to development and genetics in men and women ages 10 – 30 years old. The project will enroll three study groups: individuals with schizophrenia, individuals at clinical risk for developing psychosis, and healthy controls.
Variability in Response to Non-steroidal Anti-inflammatory Drugs
The purpose of this research study is to measure the difference in response to non-steroidal anti-inflammatory drugs (NSAIDs) among people. We will also study what factors, like age, sex, or genetic background, cause these differences.
Interaction of Estrogen and Serotonin in Modulating Brain Activity in Menopause
The purpose of the study is to look at the relationship between different types of early life issues and how your brain functions as an adult. There is some evidence to show that early life stress can lead to many different types of health outcomes as an adult such as ...
Investigating the Impact of Childhood Adversity on Brain Activity in Post-Menopausal Women
The aim of this study is to further our understanding of the impact of prepubertal adverse childhood experiences on brain activation during performance of affective and cognitive processing and memory tasks in men post-menopausal women between the ages of 48 and 65. Using functional brain imaging, we will identify differences ...
Startle Response in Women with Premenstrual Mood Disorders
This study examines stress response in women with premenstrual mood changes (PMDs) versus women without PMDs and men. We are looking for women with and without PMDs, and for men. For this study, you will be asked to fill out forms about your physical and mental health, have blood and ...
A brief treatment on PTSD symptoms in pregnancy
The purpose of this research study is to determine whether a new psychotherapy treatment for partial or mild PTSD symptoms can help alleviate PSTD or accompanying depressive symptoms in pregnant women. Pregnant women without PTSD symptoms are also needed as a comparison population. All healthy, pregnant women up to 34 ...